Is Oral Lichen Planus premalignant condition?

Oral lichen planus (OLP) is a common mucosal condition that is considered premalignant by some, although others argue that only lichenoid lesions with dysplasia are precancerous.

What’s the difference between premalignant lesion and premalignant condition?

The WHO has defined a precancerous lesion as “a morphologically altered tissue in which cancer is more likely to occur than in its apparently normal counterpart,” whereas a premalignant condition is defined as “a generalized state associated with a significantly increased risk of cancer” [1].

WHO classification premalignant lesions and conditions?

Under the widely used World Health Organization (WHO) classification for the pathological diagnosis of oral premalignant lesions, dysplasia, which is graded as mild, moderate or severe, and carcinoma in situ (CIS), which is a non-invasive carcinoma, are classified as precursor lesions of oral squamous cell carcinoma.

What lesion is most commonly considered premalignant?

(1) Leukoplakia and erythroplakia are two clinical lesions widely considered to be premalignant.

Which type of lichen planus is malignant?

Oral lichen planus (OLP) is a chronic inflammatory disease of unknown etiology with significant impact on patients’ quality of life. Malignant transformation into oral squamous cell carcinoma (OSCC) is considered as one of the most serious complications of the disease; nevertheless, controversy still persists.

Is lichen planus malignant?

This study indicates that patients with cutaneous lichen planus do not carry an increased risk of malignant transformation of the skin lesions or internally; however, there is increased risk of oral cancer.

What are premalignant conditions?

A precancerous condition is a condition or lesion involving abnormal cells which are associated with an increased risk of developing into cancer. Clinically, precancerous conditions encompass a variety of conditions or lesions with an increased risk of developing into cancer.

What is the meaning of premalignant?

(pree-muh-LIG-nunt) A term used to describe a condition that may (or is likely to) become cancer.

What are the premalignant lesions?

A precancerous lesion is “a morphologically altered tissue in which oral cancer is more likely to occur than its apparently normal counterpart.” These precancerous lesions include leukoplakia, erythroplakia, and the palatal lesions of reverse smokers.

Is syphilitic glossitis premalignant?

The term leukoplakia was first used by Schwimmer in 1877 to describe a white lesion of the tongue, which probably represented a syphilitic glossitis. It is the most common premalignant lesion (85%) and the most studied PMD.

What are the different types of oral lichen planus?

Classically present as six types cinically: Reticular (fine white striae cross each other in the lesion), Atrophic (areas of erythematous lesion surrounded by reticular components), papular type, bullous type, plaque type, erosive or ulcerative type.