Post-cardiac arrest syndrome is a clinical state that involves global brain injury, myocardial dysfunction, macrocirculatory dysfunction, increased vulnerability to infection, and persistent precipitating pathology (ie, the cause of the arrest).
What happens to people who survive cardiac arrest?
When sudden cardiac arrest occurs, reduced blood flow to your brain causes unconsciousness. If your heart rhythm doesn’t rapidly return to normal, brain damage occurs and death results. Survivors of cardiac arrest might show signs of brain damage.
What are the pathophysiologic consequences of cardiac arrest?
Pathophysiology. Cardiac arrest causes global ischemia with consequences at the cellular level that adversely affect organ function after resuscitation. The main consequences involve direct cellular damage and edema formation.
Why does the brain swell after cardiac arrest?
Conclusions: The cause of brain swelling may be related to the development of the metabolic acidosis (possibly lactic acidosis) due to hypoxia before the resuscitation period.
What are signs of post-cardiac arrest syndrome?
| Syndrome | Pathophysiology | Clinical Manifestation |
|---|---|---|
| Post–cardiac arrest brain injury | • Impaired cerebrovascular autoregulation | • Seizures |
| • Cerebral edema (limited) | • Myoclonus | |
| • Postischemic neurodegeneration | • Cognitive dysfunction | |
| • Persistent vegetative state |
What is Lance Adams syndrome?
Abstract. Lance-Adams syndrome (LAS) is a rare complication of successful cardiopulmonary resuscitation and is often accompanied by action myoclonus. LAS is seen in patients who have undergone a cardiorespiratory arrest, later regained consciousness, and then developed myoclonus days or weeks after the event.
What is life expectancy after cardiac arrest?
One year after hospital discharge, 24.5% of patients, regardless of age, had died. Survival was 18.5% at 7 years in those 70 years or older, compared with 45.4% in those aged 18 to 69 years. Heart rhythm at the time of arrest strongly influenced long-term survival.
Can the brain heal itself after cardiac arrest?
Cardiac arrest causes a primary and secondary injury. The primary injury occurs at the time of arrest and is non-reversible, and the secondary injury follows ROSC and subsequent cerebral reperfusion and is potentially reversible. The brain is exquisitely sensitive to hypoxia.
What are the signs of post-cardiac arrest syndrome?
What are non shockable rhythms?
Rhythms that are not amenable to shock include pulseless electrical activity (PEA) and asystole. In these cases, identifying primary causation, performing good CPR, and administering epinephrine are the only tools you have to resuscitate the patient.
What is Las syndrome?
